Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12947716 | 0.90 | MAPT (0.50) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL12947717 | 0.90 | MAPT (0.53) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL958384 | 0.89 | MAPT (0.53) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL12947674 | 0.88 | MAPT (0.52) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL959432 | 0.88 | MAPT (0.51) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL3402478 | 0.86 | MAPT (0.53) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL12947675 | 0.86 | MAPT (0.56) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL964198 | 0.86 | MAPT (0.56) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL958759 | 0.86 | MAPT (0.56) | MAPTALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL960344 | 0.86 | MAPT (0.48) | MAPTALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253618-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |