Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.51 |
| ▸ | CA1 | P00915 | 6/20 | 0.51 |
| ▸ | CA2 | P00918 | 6/20 | 0.51 |
| ▸ | CA9 | Q16790 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429187 | 1.00 | CA12 (0.51) | CA12CA1CA2CA9MEN1 | |
| Hydrochloric Acid SCHEMBL29396310 | 0.99 | CA12 (0.50) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL16124565 | 0.96 | CA12 (0.53) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL30466165 | 0.95 | CA12 (0.54) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL17860830 | 0.92 | MEN1 (0.49) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL22961926 | 0.88 | MEN1 (0.54) | CA12CA1CA2CA9MEN1 | |
| Hydrochloric Acid SCHEMBL9416400 | 0.86 | MEN1 (0.52) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL1429864 | 0.86 | KMT2A (0.58) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL30860183 | 0.86 | KMT2A (0.58) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL3728829 | 0.86 | KMT2A (0.58) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250164-A2 | ANGIOTENSIN II RECEPTOR BLOCKER DERIVATIVES | Nicox S.A. (FR) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009106471-A2 | NEW ANGIOTENSIN II RECEPTOR BLOCKER DERIVATIVES | NICOX S.A. (FR) | 2009-09-03 | — | — | WO | disclosed |