SCHEMBL3400044

SCHEMBL3400044

CCC1=Cc2c(-c3ccc(C4CCCCC4)cc3)cc(C)cc2C1[Zr](Cl)(Cl)(C1C(C)=Cc2c(-c3ccc(C4CCCCC4)cc3)cc(C)cc21)[SiH](CC)CC

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
S1PR1 P21453 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3403905 0.93 CYP3A4 (0.31) CYP3A4CYP2C9
SCHEMBL3397189 0.87 S1PR1 (0.34) S1PR1S1PR5
SCHEMBL3401429 0.87
SCHEMBL3401158 0.85
Hydrochloric Acid SCHEMBL3403906 0.85 CYP3A4 (0.31) CYP3A4CYP2C9S1PR1S1PR5
Hydrochloric Acid SCHEMBL3400047 0.85 CYP3A4 (0.31) CYP3A4CYP2C9S1PR1S1PR5
SCHEMBL3401153 0.82
SCHEMBL3397174 0.82
SCHEMBL3400253 0.82
SCHEMBL3398796 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2235071-A2 METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO AND COPOLYMERS Novolen Technology Holdings, C.V. (NL) 2010-10-06 EP claimed
WO-2009054833-A2 METALLOCENE COMPOUNDS, CATALYSTS COMPRISING THEM, PROCESS FOR PRODUCING AN OLEFIN POLYMER BY USE OF THE CATALYSTS, AND OLEFIN HOMO AND COPOLYMERS NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) 2009-04-30 WO claimed