Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400801 | 0.99 | FFAR1 (0.73) | FFAR1 | |
| SCHEMBL3400264 | 0.89 | FFAR1 (0.58) | FFAR1 | |
| SCHEMBL3398191 | 0.88 | FFAR1 (0.77) | FFAR1 | |
| SCHEMBL3403140 | 0.86 | FFAR1 (0.57) | FFAR1 | |
| SCHEMBL13616549 | 0.85 | FFAR1 (0.97) | FFAR1 | |
| SCHEMBL3403093 | 0.85 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL3395420 | 0.84 | FFAR1 (0.57) | FFAR1 | |
| SCHEMBL3398419 | 0.84 | FFAR1 (0.57) | FFAR1 | |
| SCHEMBL3403219 | 0.84 | FFAR1 (0.57) | FFAR1 | |
| SCHEMBL3398628 | 0.84 | FFAR1 (0.57) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2684861-A2 | Spiro compounds and pharmaceutical use thereof | Japan Tobacco Inc. (JP) | 2014-01-15 | — | — | EP | disclosed |
| EP-2508503-A1 | Spiro compounds and pharmaceutical use thereof | Japan Tobacco, Inc. (JP) | 2012-10-10 | — | — | EP | disclosed |
| EP-2202216-B1 | SPIRO-RING COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | JAPAN TOBACCO INC (JP) | 2012-06-27 | — | — | EP | disclosed |
| EP-2202216-A1 | SPIRO-RING COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | Japan Tobacco Inc. (JP) | 2010-06-30 | — | — | EP | disclosed |