Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407733 | 0.84 | S1PR1 (0.71) | S1PR1S1PR3 | |
| SCHEMBL3406959 | 0.84 | S1PR1 (0.61) | S1PR1S1PR3 | |
| SCHEMBL3402301 | 0.84 | S1PR1 (0.65) | S1PR1S1PR3 | |
| SCHEMBL3404177 | 0.83 | S1PR1 (0.79) | S1PR1S1PR3 | |
| SCHEMBL27841721 | 0.83 | S1PR1 (0.73) | S1PR1S1PR3 | |
| SCHEMBL3402276 | 0.82 | S1PR1 (0.64) | S1PR1S1PR3 | |
| SCHEMBL3402299 | 0.82 | S1PR1 (0.67) | S1PR1S1PR3 | |
| SCHEMBL3406405 | 0.81 | S1PR1 (0.62) | S1PR1S1PR3 | |
| SCHEMBL3095704 | 0.80 | S1PR1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL3405097 | 0.79 | S1PR1 (0.63) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252609-B1 | PYRIDIN-2-YL DERIVATIVES AS IMMUNOMODULATING AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-04-17 | — | — | EP | disclosed |
| EP-2252609-A1 | PYRIDIN-2-YL DERIVATIVES AS IMMUNOMODULATING AGENTS | Actelion Pharmaceuticals Ltd. (CH) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009109872-A1 | PYRIDIN-2-YL DERIVATIVES AS IMMUNOMODULATING AGENTS | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-11 | — | — | WO | disclosed |