Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1236592 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL1060325 | 0.87 | SYK (0.79) | SYK | |
| SCHEMBL1051630 | 0.87 | SYK (0.80) | SYK | |
| SCHEMBL1058515 | 0.87 | SYK (1.00) | SYK | |
| SCHEMBL1236279 | 0.86 | SYK (1.00) | SYK | |
| SCHEMBL1235113 | 0.86 | SYK (1.00) | SYK | |
| SCHEMBL1235761 | 0.86 | SYK (1.00) | SYK | |
| SCHEMBL1234881 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL1235642 | 0.85 | SYK (1.00) | SYK | |
| SCHEMBL1235010 | 0.85 | SYK (1.00) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250169-A1 | PYRIDO [4, 3-D]PYRIMIDINONE DERIVATIVES AS KINASE INHIBITORS | IRM LLC (BM) | 2010-11-17 | — | — | EP | claimed |
| WO-2009099801-A1 | PYRIDO [4, 3-D] PYRIMIDINONE DERIVATIVES AS KINASE INHIBITORS | IRM LLC (BM) | 2009-08-13 | — | — | WO | claimed |