Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | ACACA | Q13085 | 3/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405421 | 0.98 | HTR2C (0.43) | HTR2CHTR2AUSP2MEN1KMT2A | |
| SCHEMBL3402312 | 0.89 | HTR2C (0.43) | HTR2CHTR2AUSP2MEN1KMT2A | |
| SCHEMBL3403662 | 0.87 | ACACB (0.44) | HTR2CHTR2AUSP2MEN1KMT2A | |
| SCHEMBL3399637 | 0.86 | HTR2C (0.48) | HTR2CHTR2AUSP2MEN1KMT2A | |
| SCHEMBL3403025 | 0.84 | USP2 (0.49) | HTR2CHTR2AUSP2MEN1KMT2A | |
| SCHEMBL3401099 | 0.76 | GAA (0.43) | HTR2CHTR2AUSP2MEN1KMT2A | |
| SCHEMBL3402695 | 0.75 | HTR2C (0.56) | HTR2CHTR2AMEN1KMT2ALMNA | |
| SCHEMBL3401202 | 0.75 | HTR2C (0.56) | HTR2CHTR2AMEN1KMT2ALMNA | |
| SCHEMBL3405696 | 0.75 | HTR2C (0.59) | HTR2CHTR2AMEN1KMT2ALMNA | |
| SCHEMBL3401043 | 0.75 | HTR2C (0.56) | HTR2CUSP2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| US-7728009-B1 | Thiazole amides, imidazole amides and related analogues | NEUROGEN CORPORATION (US) | 2010-06-01 | — | — | US | disclosed |
| WO-2006089076-A9 | THIAZOLE AMIDES, IMIDAZOLE AMIDES AND RELATED ANALOGUES | NEUROGEN CORP (US) | 2007-04-26 | — | — | WO | disclosed |