Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1086917 | 0.85 | GAA (0.55) | GAAMAPTTP53SMN1; SMN2MAPK1 | |
| SCHEMBL1097764 | 0.83 | GAA (0.54) | GAAMAPTTP53SMN1; SMN2MAPK1 | |
| SCHEMBL2291064 | 0.77 | GAA (0.54) | GAAMAPTTP53SMN1; SMN2MAPK1 | |
| SCHEMBL1097370 | 0.77 | GAA (0.59) | GAAMAPTTP53SMN1; SMN2MAPK1 | |
| SCHEMBL2611912 | 0.74 | GAA (0.61) | GAAMAPTTP53SMN1; SMN2MAPK1 | |
| SCHEMBL2611940 | 0.73 | GAA (0.60) | GAAMAPTTP53SMN1; SMN2MAPK1 | |
| SCHEMBL2292074 | 0.73 | GAA (0.52) | GAAMAPTTP53SMN1; SMN2MAPK1 | |
| SCHEMBL2288504 | 0.73 | GAA (0.54) | GAAMAPTTP53SMN1; SMN2MAPK1 | |
| SCHEMBL2289252 | 0.73 | GAA (0.53) | GAAMAPTTP53SMN1; SMN2MAPK1 | |
| SCHEMBL16266137 | 0.73 | GAA (0.53) | GAAMAPTTP53SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097411-B1 | 3 -AMINO-IMIDAZO [1,2 -A]PYRIDINE DERIVATIVES HAVING AN SGLT1 AND SGLT2 INHIBITING ACTION, FOR TREATING TYPE 1 AND TYPE 2 DIABETES | MERCK PATENT GMBH (DE) | 2010-11-17 | — | — | EP | claimed |
| EP-2097411-B1 | 3 -AMINO-IMIDAZO [1,2 -A]PYRIDINE DERIVATIVES HAVING AN SGLT1 AND SGLT2 INHIBITING ACTION, FOR TREATING TYPE 1 AND TYPE 2 DIABETES | MERCK PATENT GMBH (DE) | 2010-11-17 | — | — | EP | disclosed |