SCHEMBL3402808

SCHEMBL3402808

CN1CC(=O)NC1=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23323359 0.76
SCHEMBL21769 0.76
SCHEMBL7217505 0.76
SCHEMBL30457088 0.75
SCHEMBL28285708 0.74
Bromide SCHEMBL4765097 0.74
Hydrochloric Acid SCHEMBL27786758 0.74
SCHEMBL20201893 0.74
SCHEMBL27570213 0.74
Ammonia Solution, Strong SCHEMBL8060626 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115989060-A Novel thiohydantoin derivatives and uses thereof 赛罗斯生物科技 2023-04-18 CN claimed
WO-2022197927-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DRUG RESISTANT TOPICAL INFECTIONS LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) 2022-09-22 WO claimed
CN-111187217-A Preparation method of high-purity 1-methyl-2-thiohydantoin 威海厚普生物科技有限公司 2020-05-22 CN claimed
CN-111655258-B Compositions for cryopreservation and methods of use thereof 常青树生物科学公司 2025-03-21 CN disclosed
CN-115989060-A Novel thiohydantoin derivatives and uses thereof 赛罗斯生物科技 2023-04-18 CN disclosed
WO-2022197927-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF DRUG RESISTANT TOPICAL INFECTIONS LANKENAU INSTITUTE FOR MEDICAL RESEARCH (US) 2022-09-22 WO disclosed
US-11433136-B2 Polyacetal polymers, conjugates, particles and uses thereof THE GENERAL HOSPITAL CORPORATION (US) 2022-09-06 US disclosed
CN-111333614-B Quinolinone compounds and use thereof 遵义医科大学珠海校区 2021-01-15 CN disclosed
CN-111333614-A Quinolinone compounds and use thereof 遵义医科大学珠海校区 2020-06-26 CN disclosed
CN-111187217-A Preparation method of high-purity 1-methyl-2-thiohydantoin 威海厚普生物科技有限公司 2020-05-22 CN disclosed
CN-111187217-A Preparation method of high-purity 1-methyl-2-thiohydantoin 威海厚普生物科技有限公司 2020-05-22 CN disclosed
EP-0449216-B1 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents WARNER LAMBERT CO (US) 1996-02-07 EP disclosed
US-5290800-A Enzyme inhibitors WARNER-LAMBERT COMPANY (US) 1994-03-01 US disclosed
US-5143928-A Inhibitors of cyclooxygenase and lipoxygenase WARNER-LAMBERT COMPANY (US) 1992-09-01 US disclosed
EP-0449216-A1 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents WARNER-LAMBERT COMPANY (US) 1991-10-02 EP disclosed
EP-0427942-A2 Process for the preparation of s-triazine-sulfenimides and their use Degussa Aktiengesellschaft (DE) 1991-05-22 EP disclosed
EP-0098456-B1 PEPTIDES COMPRISING A (1S,2R,3R)- OR (1R,2S,3S)-1-NITRILO-1-CARBONYL-3-METHYL-2-OXY-HEPTANE OR -HEPT-5-ENE RESIDUE USEFUL IN THE TOTAL SYNTHESIS OF CYCLOSPORINS, AND PROCESSES FOR THEIR PRODUCTION SANDOZ AG (CH) 1989-05-24 EP disclosed
EP-0239813-A2 Use of substituted N-trichloromethylthiohydantoins in combination with bis-(2,4-diamino-s-triazin-6-yl)-oligosulfides in vulcanizable rubber compositions, and such rubber compositions Degussa Aktiengesellschaft (DE) 1987-10-07 EP disclosed
EP-0098457-B1 (1S,2R,3R)- AND (1R,2S,3S)-NITRILO-1-CARBONYL-3-METHYL-2-OXY-HEPTANES AND -HEPT-5-ENES USEFUL IN THE TOTAL SYNTHESIS OF CYCLOSPORINS AND PROCESSES FOR THEIR PRODUCTION SANDOZ AG (CH) 1987-08-05 EP disclosed
US-4088751-A SHAVING CREAM, SHAMPOO, LOTION, 2-THIO-4-OXYPYRIMIDINE OR THIOHYDANTOIN AND HYDROGEN PEROXIDE, EXOTHERMIC REDOX REACTION COLGATE-PALMOLIVE COMPANY (US) 1978-05-09 US disclosed