Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 14/20 | 0.41 |
| ▸ | ESR1 | P03372 | 10/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2397415 | 0.78 | ESR2 (0.68) | ESR2ESR1 | |
| SCHEMBL2399693 | 0.78 | ESR2 (0.53) | ESR2ESR1CEPT1 | |
| SCHEMBL2399042 | 0.77 | ESR2 (0.67) | ESR2ESR1 | |
| Ammonia Solution, Strong SCHEMBL2400488 | 0.77 | ESR2 (0.67) | ESR2ESR1 | |
| SCHEMBL2400099 | 0.77 | ESR2 (0.67) | ESR2ESR1 | |
| SCHEMBL3404971 | 0.77 | ESR2 (0.47) | ESR2ESR1CEPT1CETPHDAC6 | |
| Ammonia Solution, Strong SCHEMBL2400492 | 0.77 | ESR2 (0.67) | ESR2ESR1 | |
| SCHEMBL12266842 | 0.73 | ESR2 (0.50) | ESR2ESR1CEPT1CETP | |
| SCHEMBL12266846 | 0.70 | ESR2 (0.66) | ESR2ESR1 | |
| SCHEMBL2399045 | 0.69 | ESR2 (0.67) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250180-A1 | PHOSPHATE DERIVATIVES OF SUBSTITUTED BENZOXAZOLES | Wyeth LLC (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009100335-A1 | PHOSPHATE DERIVATIVES OF SUBSTITUTED BENZOXAZOLES | WYETH (US) | 2009-08-13 | — | — | WO | disclosed |