Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 14/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933972 | 0.76 | AOC3 (0.59) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3401815 | 0.76 | NPC1 (0.62) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8430108 | 0.75 | AOC3 (0.76) | AOC3NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9570944 | 0.73 | SMN1; SMN2 (0.69) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2612387 | 0.72 | SMN1; SMN2 (0.73) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10745939 | 0.72 | SMN1; SMN2 (0.60) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL971477 | 0.72 | AOC3 (0.48) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL972294 | 0.71 | AOC3 (0.61) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3933298 | 0.71 | AOC3 (0.56) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3404379 | 0.71 | AOC3 (0.43) | AOC3NPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009096609-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-08-06 | — | — | WO | disclosed |