SCHEMBL3405259

SCHEMBL3405259

O=Cc1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1

nearest known ligand 0.69

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCD O00767 14/20 0.63
DCTPP1 Q9H773 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27704765 0.84 SCD (0.58) SCDDCTPP1
SCHEMBL3845305 0.84 SCD (0.66) SCDDCTPP1
SCHEMBL1766107 0.84 SCD (0.69) SCDDCTPP1
SCHEMBL937224 0.84 SCD (0.66) SCDDCTPP1
SCHEMBL935839 0.83 SCD (0.77) SCDDCTPP1
SCHEMBL27866123 0.82 SCD (0.58) SCDDCTPP1
SCHEMBL4716305 0.82 SCD (0.58) SCDDCTPP1
SCHEMBL2008150 0.82 SCD (0.72) SCDDCTPP1
SCHEMBL3831942 0.82 SCD (0.63) SCDDCTPP1
SCHEMBL14143560 0.82 SCD (0.63) SCDDCTPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2257291-A2 PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS IN THE TREATMENT OF SKIN DISORDERS Xenon Pharmaceuticals Inc. (CA) 2010-12-08 EP disclosed
WO-2009106991-A2 PYRIDAZINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS XENON PHARMACEUTICALS INC. (CA) 2009-09-03 WO disclosed