Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | HTR4 | Q13639 | 9/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1502190 | 0.93 | KCNH2 (0.63) | KCNH2DRD3MEN1LMNACYP1A2 | |
| SCHEMBL1501953 | 0.86 | DRD3 (0.54) | KCNH2DRD3MEN1LMNACYP1A2 | |
| SCHEMBL1502145 | 0.83 | KCNH2 (0.65) | KCNH2DRD3MEN1LMNACYP1A2 | |
| SCHEMBL7371801 | 0.81 | DRD3 (0.72) | KCNH2DRD3MEN1LMNACYP1A2 | |
| SCHEMBL1502107 | 0.80 | KCNH2 (0.65) | KCNH2DRD3MEN1LMNACYP1A2 | |
| SCHEMBL1501885 | 0.80 | KCNH2 (0.66) | KCNH2DRD3MEN1LMNACYP1A2 | |
| SCHEMBL1502054 | 0.80 | KCNH2 (0.66) | KCNH2DRD3MEN1LMNACYP1A2 | |
| SCHEMBL1502298 | 0.80 | KCNH2 (0.64) | KCNH2DRD3MEN1LMNACYP1A2 | |
| SCHEMBL1502302 | 0.80 | KCNH2 (0.64) | KCNH2DRD3MEN1LMNACYP1A2 | |
| SCHEMBL1501978 | 0.80 | KCNH2 (0.68) | KCNH2DRD3MEN1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2256114-A1 | AMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2010-12-01 | — | — | EP | claimed |