Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 7/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10495910 | 1.00 | EPHX1 (0.69) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL6294164 | 1.00 | EPHX1 (0.69) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL12643420 | 1.00 | EPHX1 (0.69) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL27718439 | 1.00 | EPHX1 (0.69) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL624891 | 1.00 | EPHX1 (0.69) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL9105572 | 1.00 | EPHX1 (0.69) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL1527352 | 1.00 | EPHX1 (0.69) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL6060936 | 1.00 | EPHX1 (0.69) | EPHX1MAPTHSD17B10GMNNTP53 | |
| Methane SCHEMBL15842431 | 0.98 | EPHX1 (0.67) | EPHX1MAPTHSD17B10GMNNTP53 | |
| SCHEMBL13451122 | 0.98 | EPHX1 (0.66) | EPHX1MAPTHSD17B10GMNNTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252277-A2 | ACETYL MIMIC COMPOUNDS FOR THE INHIBITION OF ISOPRENYL-S-CYSTEINYL METHYLTRANSFERASE | Signum Biosciences, Inc. (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009102997-A2 | ACETYL MIMIC COMPOUNDS FOR THE INHIBITION OF ISOPRENYL-S-CYSTEINYL METHYLTRANSFERASE | SIGNUM BIOSCIENCES, INC. (US) | 2009-08-20 | — | — | WO | disclosed |
| US-5144045-A | Treatment of inflammatory related disorders | AMERICAN CYANAMID COMPANY (US) | 1992-09-01 | — | — | US | disclosed |