Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 18/20 | 0.65 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL974383 | 0.86 | AOC3 (0.72) | AOC3MAOBSMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL971563 | 0.85 | AOC3 (0.71) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL972829 | 0.83 | AOC3 (0.70) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL974398 | 0.82 | AOC3 (0.69) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL974395 | 0.82 | AOC3 (0.69) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL970629 | 0.82 | AOC3 (0.69) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL973258 | 0.81 | AOC3 (0.67) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL973847 | 0.81 | AOC3 (0.67) | AOC3MAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL971640 | 0.81 | AOC3 (0.74) | AOC3MAOBSMN1; SMN2KMT2A | |
| SCHEMBL3934166 | 0.80 | AOC3 (0.85) | AOC3MAOBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009096609-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-08-06 | — | — | WO | disclosed |