Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 16/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3401758 | 0.89 | AOC3 (0.54) | AOC3MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12947687 | 0.86 | AOC3 (0.54) | AOC3MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3406059 | 0.83 | AOC3 (0.49) | AOC3MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3406288 | 0.81 | NPC1 (0.58) | AOC3MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL971452 | 0.80 | AOC3 (0.61) | AOC3MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3406056 | 0.80 | AOC3 (0.48) | AOC3MAOBNPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL972158 | 0.80 | AOC3 (0.60) | AOC3MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL973533 | 0.78 | AOC3 (0.52) | AOC3MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL973606 | 0.78 | AOC3 (0.52) | AOC3MAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL16784935 | 0.78 | AOC3 (0.58) | AOC3MAOBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252604-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-Tech Ueno, Ltd. (JP) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009096609-A1 | THIAZOLE DERIVATIVE AND USE THEREOF AS VAP-1 INHIBITOR | R-TECH UENO, LTD. (JP) | 2009-08-06 | — | — | WO | disclosed |