⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3406148 | 1.00 | — | — | |
| SCHEMBL2572299 | 0.82 | PPARG (0.36) | — | |
| SCHEMBL5276835 | 0.80 | FNTA (0.40) | — | |
| SCHEMBL6035351 | 0.76 | PPARG (0.33) | — | |
| SCHEMBL11620350 | 0.74 | FNTA (0.38) | — | |
| SCHEMBL11620351 | 0.74 | FNTA (0.38) | — | |
| SCHEMBL853813 | 0.74 | — | — | |
| SCHEMBL4623652 | 0.72 | TSHR (0.37) | — | |
| SCHEMBL17748854 | 0.72 | TSHR (0.37) | — | |
| SCHEMBL4623657 | 0.72 | TSHR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252277-A2 | ACETYL MIMIC COMPOUNDS FOR THE INHIBITION OF ISOPRENYL-S-CYSTEINYL METHYLTRANSFERASE | Signum Biosciences, Inc. (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009102997-A2 | ACETYL MIMIC COMPOUNDS FOR THE INHIBITION OF ISOPRENYL-S-CYSTEINYL METHYLTRANSFERASE | SIGNUM BIOSCIENCES, INC. (US) | 2009-08-20 | — | — | WO | disclosed |