Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL3405110 | 0.99 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL5322194 | 0.96 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL2906661 | 0.88 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Water SCHEMBL3405499 | 0.87 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Hydrochloric Acid SCHEMBL6707673 | 0.87 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL6707041 | 0.86 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Hydrochloric Acid SCHEMBL6709072 | 0.85 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Hydrochloric Acid SCHEMBL6707426 | 0.85 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| SCHEMBL5971689 | 0.84 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3LMNACNR1 | |
| Hydrochloric Acid SCHEMBL6710433 | 0.83 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3LMNACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252573-A2 | NEW POLYMORPH AND AMORPHOUS FORMS OF DESVENLAFAXINE FUMARATE | Egis Gyógyszergyár Nyilvánosan Müködö (HU) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009101458-A2 | NEW POLYMORPH AND AMORPHOUS FORMS OF DESVENLAFAXINE FUMARATE | EGIS GYÓGYSZERGYÁR NYILVÁNOSAN MŰKÖDŐ (HU) | 2009-08-20 | — | — | WO | disclosed |