Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GUSB | P08236 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 5/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 4/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21192480 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1HSD17B10TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL29756564 | 0.83 | GUSB (0.44) | ALDH1A1HSD17B10TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL251077 | 0.83 | GUSB (0.44) | ALDH1A1HSD17B10TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL13488050 | 0.81 | PDK2 (0.40) | ALDH1A1HSD17B10TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL13488086 | 0.78 | PDK2 (0.40) | ALDH1A1HSD17B10TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL13487898 | 0.77 | PDK2 (0.42) | ALDH1A1HSD17B10TSHRSMN1; SMN2HPGD | |
| SCHEMBL10353273 | 0.77 | KDM4E (0.46) | ALDH1A1HSD17B10TSHRSMN1; SMN2CYP1A2 | |
| SCHEMBL27070858 | 0.76 | PDK2 (0.39) | TSHRCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12247010 | 0.76 | KDM4E (0.37) | ALDH1A1HSD17B10TSHRSMN1; SMN2CYP2C9 | |
| SCHEMBL10353361 | 0.76 | SMN1; SMN2 (0.45) | ALDH1A1HSD17B10TSHRSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010040777-A1 | SILOLES SUBSTITUTED WITH CONDENSED RING SYSTEMS AND USE THEREOF IN ORGANIC ELECTRONICS | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2010-04-15 | — | — | WO | disclosed |