Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 14/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2296286 | 0.87 | SCD (0.58) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL3404860 | 0.86 | SCD (0.58) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL3406866 | 0.85 | SCD (0.52) | SCD | |
| SCHEMBL3409272 | 0.84 | SCD (0.49) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL3402329 | 0.82 | SCD (0.49) | SCD | |
| SCHEMBL2290176 | 0.81 | SCD (0.57) | SCD | |
| SCHEMBL2298045 | 0.77 | SCD (0.77) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL2295558 | 0.77 | SCD (0.59) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL4092350 | 0.76 | SCD (0.73) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL12194911 | 0.76 | SCD (0.57) | SCDCYP2C9CYP2C19HTR2BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152711-B1 | 2 -HETEROARYL- PYRROLO [3, 4-C]PYRROLE DERIVATIVES AND THEIR USE AS SCD INHIBITORS | SANOFI AVENTIS (FR) | 2010-11-24 | — | — | EP | disclosed |