Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6521493 | 0.88 | F2 (0.37) | F2RIPK1DDR1TP53HRH3 | |
| SCHEMBL3409864 | 0.86 | F2 (0.38) | F2DDR1TP53HRH3SLC6A9 | |
| SCHEMBL3401787 | 0.86 | F2 (0.39) | F2RIPK1DDR1TP53HRH3 | |
| SCHEMBL3406663 | 0.85 | DDR1 (0.38) | F2RIPK1DDR1TP53 | |
| SCHEMBL3406126 | 0.84 | F2 (0.38) | F2RIPK1DDR1TP53HRH3 | |
| SCHEMBL976717 | 0.84 | F2 (0.39) | F2RIPK1DDR1TP53HRH3 | |
| SCHEMBL3661828 | 0.83 | F2 (0.37) | F2RIPK1DDR1TP53HRH3 | |
| SCHEMBL6525306 | 0.83 | F2 (0.35) | F2DDR1TP53HRH3SLC6A9 | |
| SCHEMBL3655106 | 0.83 | F2 (0.38) | F2RIPK1DDR1TP53HRH3 | |
| SCHEMBL3662481 | 0.82 | F2 (0.37) | F2RIPK1DDR1TP53GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254862-A2 | AZETIDINE-DERIVED COMPOUNDS, PREPARATION METHOD THEREFOR AND THERAPEUTIC USE OF SAME | Sanofi-Aventis (FR) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009118473-A2 | AZETIDINE-DERIVED COMPOUNDS, PREPARATION METHOD THEREFOR AND THERAPEUTIC USE OF SAME | SANOFI-AVENTIS (FR) | 2009-10-01 | — | — | WO | disclosed |