Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 1.00 |
| ▸ | CNR1 | P21554 | 10/20 | 0.81 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408129 | 1.00 | CNR2 (1.00) | CNR2CNR1P2RX7THRB | |
| SCHEMBL3413432 | 0.90 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL3413436 | 0.90 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL3406882 | 0.86 | CNR2 (0.75) | CNR2CNR1P2RX7THRB | |
| SCHEMBL3406886 | 0.86 | CNR2 (0.75) | CNR2CNR1P2RX7THRB | |
| SCHEMBL9895909 | 0.76 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL9895230 | 0.74 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL3411192 | 0.74 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL843172 | 0.74 | CNR2 (0.57) | CNR2CNR1 | |
| SCHEMBL3412482 | 0.73 | CNR2 (1.00) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261211-A1 | 1,4-dihydropyridine derivatives and their uses | Université de Lille 2 Droit et Santé (FR) | 2010-12-15 | — | — | EP | disclosed |