SCHEMBL3408149

SCHEMBL3408149

Cc1c(NC(=O)c2ccc(OCCC3CC3)cc2F)ccc2cc(CN[C@H]3CC[S@@+]([O-])CC3)cnc12

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL929557 1.00 MCHR1 (0.53) MCHR1
SCHEMBL929556 1.00 MCHR1 (0.53) MCHR1
SCHEMBL927717 0.93 MCHR1 (0.52) MCHR1
SCHEMBL929297 0.93 MCHR1 (0.52) MCHR1
SCHEMBL927719 0.93 MCHR1 (0.52) MCHR1
SCHEMBL927596 0.90 MCHR1 (0.56) MCHR1
SCHEMBL927294 0.89 MCHR1 (0.54) MCHR1
SCHEMBL927295 0.89 MCHR1 (0.54) MCHR1
SCHEMBL927936 0.89 MCHR1 (0.67) MCHR1
SCHEMBL927916 0.89 MCHR1 (0.67) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2261213-A1 HETEROCYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2010-12-15 EP disclosed