SCHEMBL3408235

SCHEMBL3408235

C=C(F)C(O)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20591244 0.76
SCHEMBL26574 0.76
SCHEMBL776535 0.76
SCHEMBL15074897 0.73
Ammonia Solution, Strong SCHEMBL17800250 0.73
SCHEMBL1501396 0.73
Ethylene SCHEMBL6657822 0.73
Fluoride SCHEMBL21137227 0.73
SCHEMBL3434802 0.73
Hydrochloric Acid SCHEMBL28253747 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11407692-B2 Method for oxidative cleavage of compounds with unsaturated double bond NATIONAL TSING HUA UNIVERSITY (TW) 2022-08-09 US claimed
US-20210206702-A1 METHOD FOR OXIDATIVE CLEAVAGE OF COMPOUNDS WITH UNSATURATED DOUBLE BOND NATIONAL TSING HUA UNIVERSITY (TW) 2021-07-08 US claimed
EP-1339733-B1 METHOD FOR THE PRODUCTION OF 4-(17ALPHA-METHYL SUBSTITUTED 3-OXOESTRA-4,9-DIEN-11BETA-YL)BENZALDEHYD-(1E OR 1Z)-OXIMES BAYER SCHERING PHARMA AG (DE) 2008-08-13 EP claimed
US-7268241-B2 Method for the production of 4-(17$g(a)-methyl substituted 3-oxoestra-4 9-dien-11$g(b)-yl)benzaldehyd-(1e or 1z)-oximes SCHERING AG (DE) 2007-09-11 US claimed
US-11407692-B2 Method for oxidative cleavage of compounds with unsaturated double bond NATIONAL TSING HUA UNIVERSITY (TW) 2022-08-09 US disclosed
US-20210206702-A1 METHOD FOR OXIDATIVE CLEAVAGE OF COMPOUNDS WITH UNSATURATED DOUBLE BOND NATIONAL TSING HUA UNIVERSITY (TW) 2021-07-08 US disclosed
EP-2266977-B1 2,4-di[(hetero)arylamino]-pyrimidine derivatives as zap-70 and/or syk inhibitors NOVARTIS AG (CH) 2014-05-14 EP disclosed
US-8283356-B2 2,4- Di(hetero)-arylamino-pyrimidine derivatives as ZAP-70 and/or SYK inhibitors NOVARTIS AG (CH) 2012-10-09 US disclosed
EP-2266977-A1 2,4-di[(hetero)arylamino]-pyrimidine derivatives as zap-70 and/or syk inhibitors Novartis AG (CH) 2010-12-29 EP disclosed
US-20100152182-A1 2,4- Di(hetero)-arylamino-pyrimidine Derivatives as ZAP-70 and/or SYK inhibitors NOVARTIS AG (CH) 2010-06-17 US disclosed
US-7671063-B2 2,4 Di (hetero) -arylamino-pyrimidine derivatives as ZAP-70 and/or syk inhibitors NOVARTIS AG (CH) 2010-03-02 US disclosed
US-20090042888-A1 Prostaglandin endoperoxide H synthase biosynthesis inhibitors BLACK LAWRENCE A 2009-02-12 US disclosed
EP-0937717-B1 FLUORINATED TRIALLYL ISOCYANURATES, VULCANIZABLE ELASTOMER COMPOSITIONS CONTAINING THE SAME, AND METHOD FOR VULCANIZATION DAIKIN IND LTD (JP) 2002-09-11 EP disclosed
US-20020028938-A1 Prostaglandin endoperoxide H synthase biosynthesis inhibitors BLACK LAWRENCE A (US) 2002-03-07 US disclosed
US-20020013318-A1 Prostaglandin endoperoxide H synthase biosynthesis inhibitors BLACK LAWRENCE A (US) 2002-01-31 US disclosed
US-6307047-B1 PYRIDAZINONE COMPOUNDS; INHIBITORS OF CYCLOOXYGENASE-2 (COX-2); SELECTIVITY OF THESE COMPOUNDS FOR COX-2 MINIMIZES THE UNWANTED GI AND RENAL SIDE-EFFECTS SEEN WITH CURRENTLY MARKETED NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ABBOTT LABORATORIES 2001-10-23 US disclosed
EP-1124804-A1 PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS ABBOTT LABORATORIES (US) 2001-08-22 EP disclosed
US-6191233-B1 TRIALLYL ISOCYANURATE CONTAINING FLUORINE ATOMS IS USED AS CURING AID FOR FLUOROPOLYMERS, USEFUL FOR IMPROVING HEAT RESISTANCE, MECHANICAL PROPERTIES, WEATHERPROOFING AND HYDROLYSIS RESISTANCE DAIKIN INDUSTRIES LTD. (JP) 2001-02-20 US disclosed
WO-2000024719-A1 PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS ABBOTT LABORATORIES (US) 2000-05-04 WO disclosed
EP-0937717-A1 FLUORINATED TRIALLYL ISOCYANURATES, VULCANIZABLE ELASTOMER COMPOSITIONS CONTAINING THE SAME, AND METHOD FOR VULCANIZATION DAIKIN INDUSTRIES, LIMITED (JP) 1999-08-25 EP disclosed