Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.61 |
| ▸ | CNR1 | P21554 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3408272 | 0.87 | CNR2 (0.64) | CNR2CNR1 | |
| SCHEMBL3412924 | 0.87 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL3407492 | 0.86 | CNR2 (0.63) | CNR2CNR1 | |
| SCHEMBL3410243 | 0.84 | CNR2 (0.60) | CNR2CNR1MEN1GLAKMT2A | |
| SCHEMBL11329850 | 0.83 | NPSR1 (0.54) | MEN1GLAKMT2ANPSR1ALDH1A1 | |
| SCHEMBL11324500 | 0.82 | NPSR1 (0.53) | MEN1GLAKMT2ANPSR1ALDH1A1 | |
| SCHEMBL28822165 | 0.77 | CNR1 (0.52) | CNR2CNR1MEN1GLAKMT2A | |
| SCHEMBL859605 | 0.76 | CNR2 (0.66) | CNR2CNR1 | |
| SCHEMBL3408164 | 0.76 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL843912 | 0.76 | CNR2 (0.67) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261211-A1 | 1,4-dihydropyridine derivatives and their uses | Université de Lille 2 Droit et Santé (FR) | 2010-12-15 | — | — | EP | disclosed |