SCHEMBL3410360

SCHEMBL3410360

CCOOCCOc1nc(N)c2[nH]c(=O)n(CC3CCOCC3)c2n1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.79
TLR8 Q9NR97 7/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2200486 0.91 TLR7 (0.80) TLR7TLR8
SCHEMBL2198843 0.89 TLR7 (0.80) TLR7TLR8
SCHEMBL2199666 0.88 TLR7 (1.00) TLR7TLR8
SCHEMBL2198285 0.86 TLR7 (0.76) TLR7TLR8
SCHEMBL2199219 0.86 TLR7 (0.78) TLR7TLR8
SCHEMBL2199462 0.85 TLR7 (0.77) TLR7TLR8
SCHEMBL2199297 0.84 TLR7 (0.79) TLR7TLR8
SCHEMBL2198414 0.83 TLR7 (0.71) TLR7TLR8
SCHEMBL2196460 0.83 TLR7 (0.74) TLR7TLR8
SCHEMBL13361643 0.83 TLR7 (0.89) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2125792-B1 PURINE DERIVATIVES AS IMMUNOMODULATORS GLAXOSMITHKLINE LLC (US) 2010-12-01 EP claimed