Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 18/20 | 0.51 |
| ▸ | SLC5A1 | P13866 | 11/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409070 | 1.00 | SLC5A2 (0.51) | SLC5A2SLC5A1ADRB2CHRM2CHRM4 | |
| SCHEMBL3410762 | 0.90 | SLC5A2 (0.56) | SLC5A2SLC5A1ADRB2CHRM2CHRM4 | |
| SCHEMBL3412682 | 0.90 | SLC5A2 (0.56) | SLC5A2SLC5A1ADRB2CHRM2CHRM4 | |
| SCHEMBL3413668 | 0.87 | SLC5A2 (0.62) | SLC5A2SLC5A1ADRB2CHRM2CHRM4 | |
| SCHEMBL3406574 | 0.87 | SLC5A2 (0.62) | SLC5A2SLC5A1ADRB2CHRM2CHRM4 | |
| SCHEMBL13122858 | 0.86 | SLC5A2 (0.65) | SLC5A2SLC5A1 | |
| SCHEMBL3410755 | 0.82 | SLC5A2 (0.49) | SLC5A2SLC5A1ADRB2CHRM2CHRM4 | |
| SCHEMBL3409074 | 0.82 | SLC5A2 (0.49) | SLC5A2SLC5A1ADRB2CHRM2CHRM4 | |
| SCHEMBL4417878 | 0.82 | SLC5A2 (0.49) | SLC5A2SLC5A1ADRB2CHRM2CHRM4 | |
| SCHEMBL3409072 | 0.82 | SLC5A2 (0.49) | SLC5A2SLC5A1ADRB2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105165-A1 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | URBANSKI MAUD | 2009-04-23 | — | — | US | claimed |
| US-7094764-B2 | Substituted benzimidazole-, Benztriazole-, and benzimidazolone-O-glucosides | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-08-22 | — | — | US | claimed |
| US-7816330-B2 | Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-19 | — | — | US | disclosed |
| US-20100004188-A1 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | URBANSKI MAUD | 2010-01-07 | — | — | US | disclosed |
| EP-1679966-A4 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | JANSSEN PHARMACEUTICA NV (BE) | 2009-05-27 | — | — | EP | disclosed |
| US-20090105165-A1 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | URBANSKI MAUD | 2009-04-23 | — | — | US | disclosed |
| US-20060234954-A1 | Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides | Tanabe Pharma Corporation (JP) | 2006-10-19 | — | — | US | disclosed |
| US-7094764-B2 | Substituted benzimidazole-, Benztriazole-, and benzimidazolone-O-glucosides | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-08-22 | — | — | US | disclosed |
| EP-1679966-A2 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-07-19 | — | — | EP | disclosed |
| US-20050032712-A1 | Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-10 | — | — | US | disclosed |
| WO-2005012242-A2 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | JANSSEN PHARMACEUTICA NV (BE) | 2005-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105165-A1 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | GANAB, GCG, B3GAT3 | SLC5A2 16/4885SLC5A1 18/4885ADRB2 2619/4885 |
| US-20050032712-A1 | Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides | GANAB, GCG, GANC | SLC5A2 18/4885SLC5A1 19/4885ADRB2 2630/4885 |
| US-20100004188-A1 | SUBSTITUTED BENZIMIDAZOLE-, BENZTRIAZOLE-, AND BENZIMIDAZOLONE-O-GLUCOSIDES | GANAB, GCG, GANC | SLC5A2 18/4885SLC5A1 19/4885ADRB2 2630/4885 |
| US-20060234954-A1 | Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides | GANAB, GCG, B3GAT3 | SLC5A2 16/4885SLC5A1 17/4885ADRB2 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.