Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2931501 | 1.00 | HCRTR1 (0.56) | HCRTR1HCRTR2TP53MAPT | |
| SCHEMBL2929530 | 1.00 | HCRTR1 (0.56) | HCRTR1HCRTR2TP53MAPT | |
| SCHEMBL2931500 | 1.00 | HCRTR1 (0.56) | HCRTR1HCRTR2TP53MAPT | |
| SCHEMBL1340559 | 1.00 | HCRTR1 (0.56) | HCRTR1HCRTR2TP53MAPT | |
| SCHEMBL1340563 | 1.00 | HCRTR1 (0.56) | HCRTR1HCRTR2TP53MAPT | |
| SCHEMBL2927553 | 0.95 | HCRTR1 (0.54) | HCRTR1HCRTR2MAPT | |
| SCHEMBL2927550 | 0.95 | HCRTR1 (0.54) | HCRTR1HCRTR2MAPT | |
| SCHEMBL2927555 | 0.95 | HCRTR1 (0.54) | HCRTR1HCRTR2MAPT | |
| SCHEMBL2930473 | 0.94 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL2930469 | 0.94 | HCRTR1 (0.55) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185512-B1 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-12-29 | — | — | EP | claimed |