SCHEMBL3412464

SCHEMBL3412464

CCCCCC(C)(C)Oc1ccc(-n2nc3ccccc3n2)c(O)c1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
LMNA P02545 1/20 0.39
CNR1 P21554 8/20 0.36
CNR2 P34972 8/20 0.36
KDM4E B2RXH2 2/20 0.36
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
GAA P10253 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
ALDH1A1 P00352 2/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5147792 0.91 NPC1 (0.48) NPC1RAB9ALMNACNR1CNR2
SCHEMBL8857110 0.83 NPC1 (0.43) NPC1RAB9ALMNAKDM4EMAPT
SCHEMBL3887357 0.82 CNR1 (0.53) NPC1RAB9ALMNACNR1CNR2
SCHEMBL29463600 0.81 GPBAR1 (0.46) NPC1RAB9ALMNAKDM4EMAPT
SCHEMBL7141357 0.81 GPBAR1 (0.46) NPC1RAB9ALMNAKDM4EMAPT
SCHEMBL23222459 0.81 NPC1 (0.48) NPC1RAB9ALMNAKDM4EMAPT
SCHEMBL13370102 0.81 NR5A1 (0.50) NPC1RAB9ALMNACNR2KDM4E
SCHEMBL45837 0.81 NR5A1 (0.50) NPC1RAB9ALMNACNR2KDM4E
SCHEMBL5445426 0.81 NR5A1 (0.50) NPC1RAB9ALMNACNR2KDM4E
SCHEMBL9744615 0.81 NR5A1 (0.50) NPC1RAB9ALMNACNR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2554608-B1 METALLIC PIGMENT COMPOSITION ASAHI CHEMICAL IND (JP) 2018-12-26 EP disclosed
EP-2565238-B1 METALLIC-PIGMENT COMPOSITION ASAHI CHEMICAL IND (JP) 2017-08-23 EP disclosed
EP-2581419-B1 METALLIC PIGMENT COMPOSITION ASAHI KASEI CHEMICALS CORP (JP) 2016-10-05 EP disclosed
US-9296906-B2 Metallic pigment composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2016-03-29 US disclosed
US-9017475-B2 Metal pigment composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-04-28 US disclosed
EP-2581419-A1 METALLIC PIGMENT COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-04-17 EP disclosed
US-20130078438-A1 METALLIC PIGMENT COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-03-28 US disclosed
EP-2565238-A1 METALLIC-PIGMENT COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-03-06 EP disclosed
EP-2554608-A1 METALLIC PIGMENT COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-02-06 EP disclosed
US-20100000445-A1 Metal Pigment Composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-01-07 US disclosed
EP-0115940-B2 Film-forming propylene copolymer, film thereof and process for production of the film MITSUI PETROCHEMICAL IND (JP) 1997-03-19 EP disclosed
US-4668753-A EHTYLENE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-05-26 US disclosed
EP-0115940-B1 FILM-FORMING PROPYLENE COPOLYMER, FILM THEREOF AND PROCESS FOR PRODUCTION OF THE FILM MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-12-30 EP disclosed
EP-0172961-A1 1-Butene polymer and its use MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-03-05 EP disclosed
EP-0115940-A1 Film-forming propylene copolymer, film thereof and process for production of the film MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-08-15 EP disclosed