Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3411996 | 1.00 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL2931068 | 1.00 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL2447475 | 0.94 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2445171 | 0.90 | HCRTR1 (0.55) | HCRTR1HCRTR2 | |
| SCHEMBL2930078 | 0.89 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL3413297 | 0.89 | HCRTR1 (0.47) | HCRTR1HCRTR2 | |
| SCHEMBL3417701 | 0.89 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL3414370 | 0.89 | HCRTR1 (0.49) | HCRTR1HCRTR2 | |
| SCHEMBL2927774 | 0.88 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL2799726 | 0.88 | HCRTR1 (0.56) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185512-B1 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-12-29 | — | — | EP | claimed |
| EP-2185512-A2 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-05-19 | — | — | EP | claimed |
| WO-2009016560-A2 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-02-05 | — | — | WO | claimed |
| EP-2185512-B1 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-12-29 | — | — | EP | disclosed |
| EP-2185512-A2 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009016560-A2 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-02-05 | — | — | WO | disclosed |