SCHEMBL3412899

SCHEMBL3412899

CN(C)c1ccc2c(c1)Sc1cc(N(C)C)ccc1N2Nc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
MAPK1 P28482 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
SNCA P37840 2/20 0.47
BCHE P06276 3/20 0.36
KCNK3 O14649 1/20 0.35
KDM1A O60341 1/20 0.35
CYP1A2 P05177 1/20 0.34
PDGFRB P09619 1/20 0.34
ACHE P22303 1/20 0.34
ALDH1A1 P00352 3/20 0.33
ADRA2A P08913 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
GAA P10253 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3415950 0.79 SNCA (0.53) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL3414666 0.78 MEN1 (0.45) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL23954330 0.76 MEN1 (0.58) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL22300775 0.75 SNCA (0.46) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL3310949 0.75 BCHE (0.51) MEN1KMT2ABCHECYP1A2ACHE
SCHEMBL3419052 0.73 SNCA (0.76) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL9560319 0.73 SNCA (0.66) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL23999391 0.72 SNCA (0.55) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL14593435 0.72 MAPK1 (0.56) MEN1KMT2AL3MBTL1MAPK1TDP1
SCHEMBL25028322 0.71 MEN1 (0.56) MEN1KMT2AL3MBTL1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838304-B2 Liquid reagent of color former and method of stabilizing the same ARKRAY, INC. (JP) 2010-11-23 US disclosed
US-20090053823-A1 Liquid Reagent of Color Former and Method of Stabilizing The Same ARKRAY, INC. (JP) 2009-02-26 US disclosed
EP-1985670-A1 LIQUID REAGENT OF COLOR FORMER AND METHOD OF STABILIZING THE SAME Arkray, Inc. (JP) 2008-10-29 EP disclosed