2-Phenyl-1H-Indole

2-Phenyl-1H-Indole

SCHEMBL341378

c1ccc(-c2cc3ccccc3[nH]2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 1.00
RAB9A P51151 5/20 1.00
KDM4E B2RXH2 5/20 0.71
MAPT P10636 4/20 0.71
MEN1 O00255 4/20 0.71
KMT2A Q03164 4/20 0.71
CASP3 P42574 3/20 0.71
SENP8 Q96LD8 3/20 0.71
SENP7 Q9BQF6 3/20 0.71
SENP6 Q9GZR1 3/20 0.71
ALDH1A1 P00352 2/20 0.71
CYP1A2 P05177 2/20 0.71
HPGD P15428 2/20 0.71
CYP2C9 P11712 1/20 0.71
CYP2C19 P33261 1/20 0.71
CYP19A1 P11511 5/20 0.65
LMNA P02545 2/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Phenyl-1H-Indole SCHEMBL29363616 1.00 NPC1 (1.00) NPC1RAB9AKDM4EMAPTMEN1
2-Phenyl-1H-Indole SCHEMBL28844905 0.98 NPC1 (0.96) NPC1RAB9AKDM4EMAPTMEN1
2-Phenyl-1H-Indole SCHEMBL11652520 0.98 NPC1 (0.96) NPC1RAB9AKDM4EMAPTMEN1
2-Phenyl-1H-Indole SCHEMBL28371904 0.98 NPC1 (0.96) NPC1RAB9AKDM4EMAPTMEN1
2-Phenyl-1H-Indole SCHEMBL29440010 0.98 NPC1 (0.96) NPC1RAB9AKDM4EMAPTMEN1
2-Phenyl-1H-Indole SCHEMBL29788796 0.98 NPC1 (0.96) NPC1RAB9AKDM4EMAPTMEN1
2-Phenyl-1H-Indole SCHEMBL29642295 0.98 NPC1 (0.96) NPC1RAB9AKDM4EMAPTMEN1
2-Phenyl-1H-Indole SCHEMBL6529483 0.98 NPC1 (0.96) NPC1RAB9AKDM4EMAPTMEN1
2-Phenyl-1H-Indole SCHEMBL4266504 0.98 NPC1 (0.96) NPC1RAB9AKDM4EMAPTMEN1
2-Phenyl-1H-Indole SCHEMBL27928006 0.98 NPC1 (0.96) NPC1RAB9AKDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4575 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121569944-A Shepherd's purse essence and preparation method and application thereof 江西省华宝孔雀食品科技发展有限公司 2026-02-27 CN claimed
US-20250332581-A1 ARTIFICIAL PHOTOSYNTHESIS USING TITANIUM, ZIRCONIUM, AND HAFNIUM TETRAHALIDE COMPLEXES WITH VISIBLE-LIGHT-ACTIVE CHROMOPHORES, INCLUDING 2-PHENYL INDOLE AND 2-PHENYL BENZOXAZOLE ARZOUMANIDIS GREGORY G (US) 2025-10-30 US claimed
US-12405533-B2 Resist underlayer film-forming composition containing substituted crosslinkable compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2025-09-02 US claimed
US-20250231489-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2025-07-17 US claimed
US-20250205247-A1 USE OF BAZEDOXIFENE FOR INCREASING MUSCLE SURVIVAL GENETHON (FR) 2025-06-26 US claimed
US-12338328-B2 Reversible stress-responsive material, preparation method, and use thereof SOUTHWEST UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2025-06-24 US claimed
US-20250154099-A1 PREPARATION METHOD OF 2-PHENYLINDOLE DERIVATIVES AND APPLICATION THEREOF SHIHEZI UNIVERSITY (CN) 2025-05-15 US claimed
CN-119998731-A Composition for forming resist underlayer film 日产化学株式会社 2025-05-13 CN claimed
WO-2025087483-A1 METHOD OF DETECTING PEPTIDES AND/OR PROTEINS MK2 BIOTECHNOLOGIES GMBH (DE) 2025-05-01 WO claimed
US-20250128238-A1 SEPARATION MEDIA CONTAINING DYES DONALDSON COMPANY, INC. 2025-04-24 US claimed
US-4282298-A OVERCOATING THE PHOTOCONDUCTIVE LAYER WITH A CHARGE TRANSFER COMPOUND OF AROMATIC POLYNUCLEAR STRUCTURE; XEROGRAPHY XEROX CORPORATION (US) 1981-08-04 US claimed
EP-0028268-A1 Stabilizer composition comprising a thio-1,3-dicarbonyl compound and a heat stabilizer, and vinyl halide polymer composition stabilized therewith S.A. Diamond Shamrock Benelux N.V. (BE) 1981-05-13 EP claimed
US-4217258-A THIOCARBONYL COMPOUND, ALKYLTIN COMPOUND, METAL CARBOXYLATE, HYDROCARBYLPHENOL ARGUS CHEMICAL CORP. (US) 1980-08-12 US claimed
US-4209440-A A PHENYLINDOLE AND A DIHYDROPYRIDINE DICARBOXYLATE LABAZ (FR) 1980-06-24 US claimed
US-4134868-A Aromatic carboxylic acid ester stabilizers for PVC resins ARGUS CHEMICAL CORPORATION (US) 1979-01-16 US claimed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US claimed
US-4067826-A POLYETHYLENE, POLYVINYL CHLORIDE; RONGALITE, CHLORINATED POLYETHYLENE EMERY GUY 1978-01-10 US claimed
US-4057530-A STABILIZERS FOR VINYL CHLORIDE POLYMERS LABAZ (FR) 1977-11-08 US claimed
US-4008193-A Stabilizer combination for halogen-containing polymers HOECHST AKTIENGESELLSCHAFT (DT) 1977-02-15 US claimed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US claimed