⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL15352770 | 0.84 | — | — | |
| Ethane SCHEMBL28639609 | 0.84 | FFAR3 (0.46) | — | |
| Chloromethane SCHEMBL28098486 | 0.84 | — | — | |
| SCHEMBL22289074 | 0.84 | — | — | |
| Methyl Alcohol SCHEMBL28085279 | 0.84 | — | — | |
| SCHEMBL9181149 | 0.84 | — | — | |
| SCHEMBL78716 | 0.84 | CA1 (0.50) | — | |
| SCHEMBL1781916 | 0.84 | — | — | |
| SCHEMBL815 | 0.84 | — | — | |
| Acetic Acid SCHEMBL3961679 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100273765-A1 | Rifamycin analogs and uses thereof | ACTIVBIOTICS, INC. | 2010-10-28 | — | — | US | disclosed |
| US-7342011-B2 | Rifamycin analogs and uses thereof | ACTIVBIOTICS, INC. (US) | 2008-03-11 | — | — | US | disclosed |
| EP-1701962-A4 | RIFAMYCIN ANALOGS AND USES THEREOF | ACTIVBIOTICS INC (US) | 2008-03-05 | — | — | EP | disclosed |
| US-7271165-B2 | Rifamycin analogs and uses thereof | ACTIVBIOTICS, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| EP-1701962-A2 | RIFAMYCIN ANALOGS AND USES THEREOF | ActivBiotics, Inc. (US) | 2006-09-20 | — | — | EP | disclosed |
| EP-1663107-A2 | RIFAMYCIN ANALOGS AND USES THEREOF | Activbiotics, Inc. (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20050197333-A1 | Rifamycin analogs and uses thereof | ACTIVBIOTICS PHARMA LLC | 2005-09-08 | — | — | US | disclosed |
| WO-2005062882-A2 | RIFAMYCIN ANALOGS AND USES THEREOF | ACTIVBIOTICS, INC (US) | 2005-07-14 | — | — | WO | disclosed |
| WO-2005020894-A2 | RIFAMYCIN ANALOGS AND USES THEREOF | ACTIVBIOTICS, INC. (US) | 2005-03-10 | — | — | WO | disclosed |
| US-20050043298-A1 | Rifamycin analogs and uses thereof | ACTIVBIOTICS PHARMA LLC | 2005-02-24 | — | — | US | disclosed |