Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247211 | 0.90 | PIK3CD (0.47) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL248314 | 0.90 | PIK3CD (0.47) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL247212 | 0.90 | PIK3CD (0.47) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL248494 | 0.81 | PIK3CD (0.49) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL10076744 | 0.81 | PIK3CD (0.49) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL246482 | 0.79 | PIK3CD (0.49) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL249839 | 0.79 | PIK3CD (0.49) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3414056 | 0.77 | PIK3CD (0.47) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL249676 | 0.77 | PIK3CD (0.47) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL250360 | 0.77 | PIK3CD (0.49) | PIK3CGPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003271-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PI3K ACTIVITY | AMGEN INC. (US) | 2012-01-05 | — | — | WO | disclosed |