Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Monoethanolamine SCHEMBL2591 | 0.96 | — | — | |
| Monoethanolamine SCHEMBL5985807 | 0.86 | — | — | |
| Monoethanolamine SCHEMBL8339880 | 0.85 | TSHR (1.00) | — | |
| Monoethanolamine SCHEMBL1332111 | 0.85 | — | — | |
| Monoethanolamine SCHEMBL10941117 | 0.85 | TSHR (1.00) | — | |
| Monoethanolamine SCHEMBL1644 | 0.85 | — | — | |
| Monoethanolamine SCHEMBL29663853 | 0.85 | — | — | |
| Monoethanolamine SCHEMBL1331364 | 0.85 | — | — | |
| Monoethanolamine SCHEMBL14675689 | 0.85 | TSHR (1.00) | — | |
| Monoethanolamine SCHEMBL4937454 | 0.85 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110078747-A | A kind of novel thiazole class drug molecule and preparation method thereof for hospital disinfection | 河南科技大学第一附属医院 | 2019-08-02 | — | — | CN | claimed |
| US-20240216521-A1 | METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES | IMMUNOGEN INC (US) | 2024-07-04 | — | — | US | disclosed |
| US-20240197898-A1 | SUBSTITUTED BENZO[5,6][1,4]DIAZEPINO[1,2-a]INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | IMMUNOGEN, INC. | 2024-06-20 | — | — | US | disclosed |
| US-20240190956-A1 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN INC (US) | 2024-06-13 | — | — | US | disclosed |
| EP-4374850-A2 | METHODS OF PREVENTING METHIONINE OXIDATION IN IMMUNOCONJUGATES | ImmunoGen, Inc. (US) | 2024-05-29 | — | — | EP | disclosed |
| US-20240165256-A1 | METHODS FOR INCREASING EFFICACY OF IMMUNOCONJUGATES TARGETING ADAM9 FOR THE TREATMENT OF CANCER | IMMUNOGEN INC (US) | 2024-05-23 | — | — | US | disclosed |
| US-RE49918-E1 | Cytotoxic benzodiazepine derivatives | IMMUNOGEN, INC. (US) | 2024-04-16 | — | — | US | disclosed |
| WO-2024059263-A1 | METHODS FOR PREPARING MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS | IMMUNOGEN, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| WO-2024059267-A1 | IMPROVED METHODS FOR PREPARING N-METHYL ALANINE ESTERS OF MAYTANSINOL | IMMUNOGEN, INC. (US) | 2024-03-21 | — | — | WO | disclosed |
| CN-117729942-A | Methods for increasing efficacy of ADAM 9-targeted immunoconjugates in the treatment of cancer | 伊缪诺金公司 | 2024-03-19 | — | — | CN | disclosed |
| US-20100203007-A1 | NOVEL BENZODIAZEPINE DERIVATIVES | IMMUNOGEN INC. (US) | 2010-08-12 | — | — | US | disclosed |
| WO-2010091150-A1 | NOVEL BENZODIAZEPINE DERIVATIVES | IMMUNOGEN, INC. (US) | 2010-08-12 | — | — | WO | disclosed |
| US-6828314-B2 | Modulation of the activity of serotonin receptors (5-HT) to treat diseases such as anxiety, depression or obesity | PFIZER | 2004-12-07 | — | — | US | disclosed |
| US-20030225058-A1 | Substituted azepino[4,5b]indoline derivatives | PHARMACIA & UPJOHN COMPANY | 2003-12-04 | — | — | US | disclosed |
| US-6586421-B2 | For therapy of central nervous system, including diseases, disorders, and conditions related to, such as anxiety, depression, hypertension, migraine, obesity, compulsive disorders, schizophrenia, autism, neurodegenerative disorders | PHARMACIA & UPJOHN COMPANY | 2003-07-01 | — | — | US | disclosed |
| EP-1319005-A2 | SUBSTITUTED AZEPINO[4,5-B]INDOLINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-06-18 | — | — | EP | disclosed |
| US-20020077318-A1 | Substituted azepino[4,5b] indoline derivatives | PHARMACIA & UPJOHN COMPANY | 2002-06-20 | — | — | US | disclosed |
| WO-2002024700-A2 | SUBSTITUTED AZEPINO[4,5b]INDOLINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2002-03-28 | — | — | WO | disclosed |
| US-4966490-A | Apparatus for use in applying a thin resinous coating to existing surfaces | HODSON CHEMICAL CONSTRUCTION CORPORATION, | 1990-10-30 | — | — | US | disclosed |
| US-4966927-A | CURABLE EPOXY RESIN FOR CONCRETE; ETHANOLAMINE-METHYLENE CHLORIDE CURING AGENT | HODSON CHEMICAL CONSTRUCTION CORPORATION, | 1990-10-30 | — | — | US | disclosed |