Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 14/20 | 0.61 |
| ▸ | PPARA | Q07869 | 6/20 | 0.59 |
| ▸ | PPARG | P37231 | 6/20 | 0.51 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413504 | 0.91 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL3415933 | 0.90 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL3414062 | 0.85 | PPARD (0.54) | PPARDPPARAPPARG | |
| SCHEMBL3415962 | 0.85 | PPARD (0.58) | PPARDPPARAPPARG | |
| SCHEMBL3417468 | 0.82 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL3418949 | 0.82 | PPARD (0.48) | PPARDPPARAPPARG | |
| SCHEMBL3419423 | 0.82 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL3413878 | 0.81 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL3418523 | 0.80 | PPARD (0.53) | PPARDPPARAPPARG | |
| SCHEMBL3416129 | 0.80 | PPARD (0.49) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| EP-1394147-A1 | CARBOXYLIC ACID DERIVATIVE AND MEDICINE COMPRISING SALT OR ESTER OF THE SAME | Eisai Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |