Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2815843 | 0.69 | TSHR (0.38) | TSHRCYP2C9KDM4EALDH1A1LMNA | |
| SCHEMBL6557963 | 0.67 | TSHR (0.48) | TSHR | |
| Adamantane SCHEMBL27604496 | 0.66 | CYP2C9 (0.50) | TSHRCYP2C9LMNAGRIN2DGRIN3B | |
| Adamantane SCHEMBL29707714 | 0.66 | CYP2C9 (0.46) | TSHRCYP2C9LMNAGRIN2DGRIN3B | |
| Adamantane SCHEMBL1527414 | 0.66 | CYP2C9 (0.46) | TSHRCYP2C9LMNAGRIN2DGRIN3B | |
| Adamantane SCHEMBL9016497 | 0.66 | CYP2C9 (0.46) | TSHRCYP2C9LMNAGRIN2DGRIN3B | |
| Adamantane SCHEMBL12761 | 0.66 | CYP2C9 (0.46) | TSHRCYP2C9LMNAGRIN2DGRIN3B | |
| SCHEMBL1072568 | 0.65 | KDM4E (0.45) | TSHRCYP2C9KDM4EALDH1A1LMNA | |
| SCHEMBL12765667 | 0.65 | TSHR (0.36) | TSHRCYP2C9KDM4EALDH1A1LMNA | |
| SCHEMBL14791313 | 0.64 | TSHR (0.40) | TSHRKDM4EALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777511-B2 | CONTACTING SOLVENT SOLUTION OF ACRYLATE POLYMER WITH AN AQUEOUS SOLUTION OF AN ACID, SUCH AS THAT OBTAINED BY DISSOLVING A POLYPROTIC CARBOXYLIC ACID, E.G., OXALIC ACID, SUCCINIC ACID, FUMARIC ACID, ETC., IN WATER. | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-08-17 | — | — | US | claimed |
| US-20100233620-A1 | Copolymer and photoresist composition including the same | CHEIL INDUSTRIES, INC. (KR) | 2010-09-16 | — | — | US | disclosed |
| WO-2009069848-A1 | NOVEL COPOLYMERS AND PHOTORESIST COMPOSITION INCLUDING THE SAME | CHEIL INDUSTRIES INC. (KR) | 2009-06-04 | — | — | WO | disclosed |
| CN-1894226-A | Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use | WYETH CORP (US) | 2007-01-10 | — | — | CN | disclosed |