Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 13/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340308 | 0.90 | HCRTR1 (0.45) | HCRTR1HCRTR2LMNA | |
| SCHEMBL3415501 | 0.87 | HCRTR1 (0.40) | HCRTR1HCRTR2 | |
| SCHEMBL3418150 | 0.86 | HCRTR1 (0.47) | HCRTR1HCRTR2LMNA | |
| SCHEMBL3415736 | 0.86 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL1571923 | 0.86 | HCRTR1 (0.42) | HCRTR1HCRTR2LMNA | |
| SCHEMBL3415522 | 0.85 | HCRTR1 (0.42) | HCRTR1HCRTR2LMNA | |
| SCHEMBL3415868 | 0.82 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL3414585 | 0.81 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL3413767 | 0.80 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL3414654 | 0.80 | HCRTR1 (0.43) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185512-B1 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-12-29 | — | — | EP | claimed |