Butyric Acid

Butyric Acid

SCHEMBL3416299

CCCC(=O)O.CCCN(C)C

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.65
HDAC3 O15379 1/20 0.65
HDAC1 Q13547 1/20 0.65
HDAC2 Q92769 1/20 0.65
HDAC8 Q9BY41 1/20 0.65
AKR1B1 P15121 1/20 0.44
KDM4C Q9H3R0 7/20 0.43
KDM5A P29375 2/20 0.43
KDM4A O75164 6/20 0.42
KDM7A Q6ZMT4 1/20 0.42
PHF8 Q9UPP1 1/20 0.42
KDM2A Q9Y2K7 1/20 0.42
GPR84 Q9NQS5 7/20 0.42
PPARG P37231 6/20 0.42
PPARD Q03181 6/20 0.42
PPARA Q07869 6/20 0.42
HDAC11 Q96DB2 5/20 0.42
TSHR P16473 4/20 0.42
ALDH1A1 P00352 2/20 0.42
TLR2 O60603 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL27812831 0.92 FFAR3 (0.52) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL8168106 0.88 FFAR3 (0.62) FFAR3HDAC3HDAC1HDAC2HDAC8
Valeric Acid SCHEMBL3414212 0.86 AKR1B1 (0.58) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL3412203 0.86 FFAR3 (0.59) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL1131411 0.86 FFAR3 (0.59) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL3412852 0.85 FFAR3 (0.65) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL3414269 0.84 FFAR3 (0.72) FFAR3HDAC3HDAC1HDAC2HDAC8
Propionic Acid SCHEMBL3410291 0.84 FFAR3 (0.56) FFAR3HDAC3HDAC1HDAC2HDAC8
Hexanoate SCHEMBL3413805 0.84 AKR1B1 (0.70) AKR1B1GPR84PPARGPPARDPPARA
Butyric Acid SCHEMBL1007031 0.84 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2265617-B1 SOLVENTS BIONIQS LTD (GB) 2014-07-02 EP claimed
EP-2265617-A1 SOLVENTS Bioniqs Limited (GB) 2010-12-29 EP claimed
WO-2009034329-A1 SOLVENTS BIONIQS LIMITED (GB) 2009-03-19 WO claimed
EP-2265617-B1 SOLVENTS BIONIQS LTD (GB) 2014-07-02 EP disclosed
EP-2265617-A1 SOLVENTS Bioniqs Limited (GB) 2010-12-29 EP disclosed
WO-2009034329-A1 SOLVENTS BIONIQS LIMITED (GB) 2009-03-19 WO disclosed