Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566185 | 0.94 | TSHR (0.61) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL13945620 | 0.86 | TSHR (0.79) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL6530911 | 0.86 | TSHR (0.59) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL244114 | 0.82 | TSHR (0.95) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL2109543 | 0.81 | TSHR (0.64) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL28584786 | 0.81 | TSHR (0.64) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL8729462 | 0.81 | TSHR (0.64) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL85963 | 0.80 | TSHR (0.75) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL16180094 | 0.80 | TSHR (0.72) | TSHRALDH1A1CYP3A4TP53HIF1A | |
| SCHEMBL16180095 | 0.80 | TSHR (0.72) | TSHRALDH1A1CYP3A4TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964862-B1 | Composition and method for preparing linear copolymers of polar and non-polar olefins free of free radical initiated polymer | ROHM & HAAS (US) | 2010-12-22 | — | — | EP | disclosed |
| US-7524912-B2 | Preparation of linear ethylene-acrylate copolymers with palladium catalysts and free radical scavengers | ROHM AND HAAS COMPANY (US) | 2009-04-28 | — | — | US | disclosed |
| EP-1964862-A1 | Composition and method for preparing linear copolymers of polar and non-polar olefins absent free radical addition polymer | Rohm and Haas Company (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1964859-A1 | A porous linear polymer composition | Rohm and Haas Company (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20080207789-A1 | Porous linear polymer composition | ACHOLLA FRANCIS V | 2008-08-28 | — | — | US | disclosed |
| US-20080207856-A1 | Composition and method for preparing copolymers of polar and non-polar olefins substantially free of free radical initiated polymer | ROHM AND HAAS COMPANY | 2008-08-28 | — | — | US | disclosed |