Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3431089 | 0.83 | MAPT (0.43) | HSP90AA1MAPTLMNAMEN1KMT2A | |
| SCHEMBL3392358 | 0.79 | MAOB (0.48) | HSP90AA1MAPTLMNAMEN1KMT2A | |
| SCHEMBL3434197 | 0.76 | SMN1; SMN2 (0.42) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL3392359 | 0.73 | F10 (0.58) | LMNAMAOBMAOA | |
| SCHEMBL3392749 | 0.72 | MAOB (0.47) | HSP90AA1MAPTLMNAMEN1KMT2A | |
| SCHEMBL3392744 | 0.72 | MAOB (0.57) | HSP90AA1LMNAMEN1KMT2AMAOB | |
| SCHEMBL3392748 | 0.70 | MAOB (0.58) | LMNAMAOBMAOA | |
| SCHEMBL3396925 | 0.70 | MAOB (0.45) | MAPTLMNAMEN1KMT2AMAOB | |
| SCHEMBL3394943 | 0.69 | MAOB (0.49) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL3392356 | 0.68 | F10 (0.59) | LMNAMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170874-A2 | NOVEL COMPOUNDS AND THEIR USE | Orchid Research Laboratories Limited (IN) | 2010-04-07 | — | — | EP | claimed |
| WO-2009001192-A2 | NOVEL COMPOUNDS AND THEIR USE | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-12-31 | — | — | WO | claimed |