SCHEMBL341793

SCHEMBL341793

Nc1ccc2c(c1)nc(-c1ccccc1)c1ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.64
ATM Q13315 2/20 0.64
TLR9 Q9NR96 2/20 0.64
MEN1 O00255 4/20 0.53
ADORA2A P29274 4/20 0.51
NUDT1 P36639 1/20 0.51
CSNK2A2 P19784 2/20 0.46
CSNK2B P67870 2/20 0.46
ACHE P22303 2/20 0.46
MAPT P10636 4/20 0.45
ALDH1A1 P00352 3/20 0.45
LMNA P02545 1/20 0.45
GPR55 Q9Y2T6 1/20 0.45
PIK3CG P48736 1/20 0.44
GAA P10253 3/20 0.44
DHFR P00374 1/20 0.42
MDM4 O15151 1/20 0.42
KDM4E B2RXH2 2/20 0.41
GLA P06280 2/20 0.41
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29460850 0.93 KMT2A (0.64) KMT2AATMTLR9MEN1ADORA2A
SCHEMBL136397 0.93 KMT2A (0.64) KMT2AATMTLR9MEN1ADORA2A
Hydrochloric Acid SCHEMBL8512975 0.92 KMT2A (0.62) KMT2AATMTLR9MEN1ADORA2A
Iodide SCHEMBL29597673 0.92 KMT2A (0.62) KMT2AATMTLR9MEN1ADORA2A
Hydrochloric Acid SCHEMBL8505910 0.92 KMT2A (0.62) KMT2AATMTLR9MEN1ADORA2A
Hydrochloric Acid SCHEMBL7049504 0.92 KMT2A (0.62) KMT2AATMTLR9MEN1ADORA2A
Iodide SCHEMBL18040116 0.92 KMT2A (0.62) KMT2AATMTLR9MEN1ADORA2A
SCHEMBL27895170 0.90 KMT2A (0.59) KMT2AATMTLR9MEN1ADORA2A
SCHEMBL14923034 0.86 KMT2A (0.55) KMT2AATMTLR9MEN1ADORA2A
SCHEMBL21131542 0.83 RAD51 (0.54) KMT2AATMTLR9MEN1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103476745-B Diamine compound containing sulfonic acid group and method for producing same NITTO DENKO CORP. (JP) 2015-09-30 CN disclosed
CN-102770408-B Novel diamine compound and production method thereof NITTO DENKO CORP 2015-05-13 CN disclosed
CN-103476832-A Polyimide, polyimide polymer electrolyte membrane, membrane electrode assembly, and solid polymer fuel cell NITTO DENKO CORP 2013-12-25 CN disclosed
CN-103476745-A Diamine compound containing sulfonic acid group and method for producing same NITTO DENKO CORP 2013-12-25 CN disclosed
CN-103459466-A Polyimide, polyimide polymer electrolyte membrane, membrane-electrode assembly, and solid polymer fuel cell NITTO DENKO CORP 2013-12-18 CN disclosed
CN-102770408-A Novel diamine compound and production method thereof NITTO DENKO CORP 2012-11-07 CN disclosed
EP-2428586-A1 Dimeric and trimeric nucleic acid dyes, and associated systems and methods Biotium Inc. (US) 2012-03-14 EP disclosed