Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412050 | 0.88 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3413926 | 0.88 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL3413929 | 0.88 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2928071 | 0.88 | HCRTR1 (0.46) | HCRTR1HCRTR2 | |
| SCHEMBL2923720 | 0.86 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL2802808 | 0.86 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL2930076 | 0.86 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL3413293 | 0.86 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL3418141 | 0.85 | HCRTR1 (0.39) | HCRTR1HCRTR2 | |
| SCHEMBL3411993 | 0.85 | HCRTR1 (0.49) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185512-B1 | TRANS-3-AZA-BICYCLO[3.1.0]HEXANE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2010-12-29 | — | — | EP | disclosed |