⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496 | 0.72 | — | — | |
| SCHEMBL15802995 | 0.70 | TSHR (0.40) | — | |
| SCHEMBL6141398 | 0.67 | — | — | |
| SCHEMBL8427777 | 0.67 | — | — | |
| SCHEMBL2123694 | 0.67 | — | — | |
| SCHEMBL27741471 | 0.67 | TSHR (0.42) | — | |
| SCHEMBL7569925 | 0.67 | — | — | |
| SCHEMBL27531737 | 0.67 | — | — | |
| SCHEMBL39635 | 0.67 | — | — | |
| SCHEMBL6790137 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976185-B1 | HECT E3 LIGASE INHIBITORS AND USES THEREOF | IFOM ST FONDAZIONE DI ONCOLOGIA MOLECOLARE ETS (IT) | 2024-02-14 | — | — | EP | claimed |
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |
| EP-2359862-B1 | Hybrid block copolymer micelles with mixed stereochemistry for encapsulation of hydrophobic agents | INTEZYNE TECHNOLOGIES INC (US) | 2013-07-24 | — | — | EP | claimed |
| EP-2073850-B1 | HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS | INTEZYNE TECHNOLOGIES INC (US) | 2010-10-27 | — | — | EP | claimed |
| EP-1907444-B1 | POLYMERIC MICELLES FOR DRUG DELIVERY | INTEZYNE TECHNOLOGIES INC (US) | 2009-08-19 | — | — | EP | claimed |
| EP-1183251-B1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA SA (ES) | 2004-02-11 | — | — | EP | claimed |
| EP-0618195-B1 | Insecticidal, acaricidal and fungicidal pyrazole phenoxyalkylamin derivatives and process for preparing the same | UBE INDUSTRIES (JP) | 1997-06-04 | — | — | EP | claimed |
| EP-0375368-B1 | Alcohol and ether derivatives | ZENECA LTD (GB) | 1995-08-16 | — | — | EP | claimed |
| EP-0385680-B1 | Heterocyclic ethers as 5-lipoxygenase inhibitors | ZENECA LTD (GB) | 1995-06-14 | — | — | EP | claimed |
| EP-0405808-B1 | Phenoxyalkylamine derivatives and insecticides, acaricides and fungicides | UBE INDUSTRIES (JP) | 1995-01-11 | — | — | EP | claimed |
| EP-0078462-B1 | 1,2,4,6-THIATRIAZINE-1,1 DIOXIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTI-GROWTH AGENTS FOR UNWANTED PLANTS | BASF Aktiengesellschaft (DE) | 1986-01-15 | — | — | EP | claimed |
| WO-1992006951-A1 | DIACETYLENE ETHERS | ISP INVESTMENTS INC. (US) | 1992-04-30 | — | — | WO | disclosed |