Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 8/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.58 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BCL2L2 | Q92843 | 4/20 | 0.50 |
| ▸ | BAD | Q92934 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420340 | 1.00 | BCL2 (0.60) | BCL2PTPN1MEN1KMT2ABCL2L1 | |
| SCHEMBL23847461 | 1.00 | BCL2 (0.60) | BCL2PTPN1MEN1KMT2ABCL2L1 | |
| SCHEMBL3420337 | 1.00 | BCL2 (0.60) | BCL2PTPN1MEN1KMT2ABCL2L1 | |
| SCHEMBL3421035 | 0.90 | MCL1 (0.52) | BCL2PTPN1MEN1KMT2ABCL2L1 | |
| SCHEMBL3421033 | 0.90 | MCL1 (0.52) | BCL2PTPN1MEN1KMT2ABCL2L1 | |
| SCHEMBL3421036 | 0.90 | MCL1 (0.52) | BCL2PTPN1MEN1KMT2ABCL2L1 | |
| SCHEMBL3420364 | 0.87 | PTPN1 (0.51) | BCL2PTPN1MEN1KMT2ABCL2L1 | |
| SCHEMBL3420358 | 0.87 | PTPN1 (0.51) | BCL2PTPN1MEN1KMT2ABCL2L1 | |
| SCHEMBL3420368 | 0.87 | PTPN1 (0.51) | BCL2PTPN1MEN1KMT2ABCL2L1 | |
| SCHEMBL3419383 | 0.87 | BCL2 (0.55) | BCL2PTPN1MEN1KMT2ABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024783-A1 | BIARYLRHODANINE AND PYRIDYLRHODANINE COMPOUNDS AND THEIR USE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2010-03-04 | — | — | WO | disclosed |