Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.89 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.89 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662656 | 1.00 | S1PR1 (0.89) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1661662 | 1.00 | S1PR1 (0.89) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL1661347 | 0.99 | S1PR1 (0.88) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL1661533 | 0.99 | S1PR1 (0.88) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL1661345 | 0.99 | S1PR1 (0.88) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1661575 | 0.94 | S1PR1 (1.00) | S1PR1S1PR3S1PR5 | |
| SCHEMBL29646247 | 0.94 | S1PR1 (1.00) | S1PR1S1PR3S1PR5 | |
| SCHEMBL30530986 | 0.94 | S1PR1 (1.00) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1663633 | 0.92 | S1PR1 (0.78) | S1PR1S1PR3S1PR5 | |
| SCHEMBL1661548 | 0.92 | S1PR1 (0.78) | S1PR1S1PR3S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306994-B1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC (US) | 2013-08-14 | — | — | EP | claimed |
| US-7842685-B2 | S1P1 receptor agonists and use thereof | AMGEN INC. (US) | 2010-11-30 | — | — | US | claimed |
| US-20100029611-A1 | S1P1 receptor agonists and use thereof | AMGEN INC. (US) | 2010-02-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029611-A1 | S1P1 receptor agonists and use thereof | S1PR1, S1PR5, S1PR2 | S1PR1 1/4885S1PR3 4/4885S1PR5 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.