Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 17/20 | 0.52 |
| ▸ | MMP3 | P08254 | 12/20 | 0.52 |
| ▸ | MMP1 | P03956 | 10/20 | 0.52 |
| ▸ | MMP7 | P09237 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28576210 | 0.89 | CSNK1E (0.54) | CNR2CSNK1EMMP2MMP3MMP1 | |
| SCHEMBL10960336 | 0.86 | FOLH1 (0.66) | CSNK1EMMP2MMP3MMP1MMP7 | |
| SCHEMBL9209348 | 0.86 | FOLH1 (0.66) | CSNK1EMMP2MMP3MMP1MMP7 | |
| SCHEMBL9655121 | 0.86 | FOLH1 (0.66) | CSNK1EMMP2MMP3MMP1MMP7 | |
| SCHEMBL9653480 | 0.86 | FOLH1 (0.66) | CSNK1EMMP2MMP3MMP1MMP7 | |
| SCHEMBL3242850 | 0.86 | FOLH1 (0.66) | CSNK1EMMP2MMP3MMP1MMP7 | |
| SCHEMBL9653477 | 0.86 | FOLH1 (0.66) | CSNK1EMMP2MMP3MMP1MMP7 | |
| SCHEMBL10955140 | 0.86 | FOLH1 (0.66) | CSNK1EMMP2MMP3MMP1MMP7 | |
| SCHEMBL10957172 | 0.86 | FOLH1 (0.66) | CSNK1EMMP2MMP3MMP1MMP7 | |
| SCHEMBL5179711 | 0.86 | FOLH1 (0.66) | CSNK1EMMP2MMP3MMP1MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1743881-B1 | Phenyl-benzyl-ketones | RUANE MICHAEL (AU) | 2010-12-22 | — | — | EP | disclosed |
| EP-1743881-A1 | Phenyl-benzyl-ketones | G.J. Consultants Pty Ltd (AU) | 2007-01-17 | — | — | EP | disclosed |