Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | DDO | Q99489 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540421 | 0.86 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4065612 | 0.84 | KDM4E (0.72) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6577224 | 0.79 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17158382 | 0.79 | MAPK14 (0.59) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7809220 | 0.78 | KDM4E (0.64) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1268537 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30804387 | 0.77 | KDM4E (0.59) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10648743 | 0.77 | MAPT (0.59) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8602933 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31206974 | 0.77 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | disclosed |