Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.66 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.63 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.62 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.60 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.59 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.59 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29761931 | 1.00 | TACR1 (0.66) | TACR1CXCR4KISS1RIL23RNTSR2 | |
| SCHEMBL29973459 | 0.97 | TACR1 (0.63) | TACR1CXCR4KISS1RIL23RNTSR2 | |
| SCHEMBL30293938 | 0.92 | TACR1 (0.65) | TACR1CXCR4KISS1RIL23RKEAP1 | |
| SCHEMBL29543021 | 0.91 | TACR1 (0.78) | TACR1KISS1RNTSR2NTSR1SORT1 | |
| SCHEMBL29535981 | 0.91 | TACR1 (0.78) | TACR1KISS1RNTSR2NTSR1SORT1 | |
| SCHEMBL29350118 | 0.91 | TACR1 (0.78) | TACR1KISS1RNTSR2NTSR1SORT1 | |
| SCHEMBL34470399 | 0.91 | NTSR2 (0.66) | TACR1CXCR4KISS1RNTSR2NTSR1 | |
| SCHEMBL29973266 | 0.91 | TACR1 (0.70) | TACR1CXCR4KISS1RIL23RNTSR2 | |
| SCHEMBL29973465 | 0.90 | TACR1 (0.59) | TACR1CXCR4KISS1RIL23RNTSR2 | |
| SCHEMBL29697181 | 0.90 | CXCR4 (0.66) | CXCR4KISS1RNTSR2NTSR1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143477-A1 | Methods and Compositions for Stimulating the Proliferation or Differentiation of Stem Cells with Substance Por an Analog Thereof | IMMUNEREGEN BIOSCIENCES, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2178550-A2 | METHODS AND COMPOSITIONS FOR STIMULATING THE PROLIFERATION OR DIFFERENTIATION OF STEM CELLS WITH SUBSTANCE P OR AN ANALOG THEREOF | Immuneregen Biosciences, Inc. (US) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009085236-A2 | COMPOSITIONS AND METHODS OF USING SUBSTANCE P. ANALOGS | IMMUNEREGEN BIOSCIENCES, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009051622-A2 | METHODS FOR STIMULATING FIBROBLAST PROLIFERATION USING SUBSTANCE P ANALOGS | IMMUNEREGEN BIOSCIENCES, INC. (US) | 2009-04-23 | — | — | WO | disclosed |
| US-20090099092-A1 | METHODS FOR STIMULATING FIBROBLAST PROLIFERATION USING SUBSTANCE P ANALOGS | IMMUNEREGEN BIOSCIENCES, INC. (US) | 2009-04-16 | — | — | US | disclosed |
| WO-2009017655-A2 | METHODS AND COMPOSITIONS FOR STIMULATING THE PROLIFERATION OR DIFFERENTIATION OF STEM CELLS WITH SUBSTANCE P OR AN ANALOG THEREOF | IMMUNEREGEN BIOSCIENCES, INC. (US) | 2009-02-05 | — | — | WO | disclosed |
| US-20090028834-A1 | Methods and compositions for stimulating the proliferation or differentiation of stem cells with substance P or an analog thereof | WILHELM, MICHAEL | 2009-01-29 | — | — | US | disclosed |