Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.95 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.95 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.95 |
| ▸ | POLB | P06746 | 2/20 | 0.95 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.79 |
| ▸ | TP53 | P04637 | 3/20 | 0.79 |
| ▸ | CA12 | O43570 | 3/20 | 0.79 |
| ▸ | CA4 | P22748 | 3/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.79 |
| ▸ | CA7 | P43166 | 3/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.79 |
| ▸ | MAPT | P10636 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | XDH | P47989 | 2/20 | 0.79 |
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | PKM | P14618 | 2/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.79 |
| ▸ | DPP4 | P27487 | 2/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Homoeriodictyol SCHEMBL2019518 | 0.99 | CYP1A1 (0.98) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 | |
| Homoeriodictyol SCHEMBL2024548 | 0.99 | CYP1A1 (0.98) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 | |
| Homoeriodictyol SCHEMBL30383489 | 0.98 | CYP1A1 (1.00) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 | |
| Homoeriodictyol SCHEMBL30016824 | 0.98 | CYP1A1 (1.00) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 | |
| Homoeriodictyol SCHEMBL2307702 | 0.98 | CYP1A1 (1.00) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 | |
| Homoeriodictyol SCHEMBL29411740 | 0.98 | CYP1A1 (1.00) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 | |
| Homoeriodictyol SCHEMBL39497 | 0.98 | CYP1A1 (1.00) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 | |
| Homoeriodictyol SCHEMBL1505910 | 0.97 | CYP1A1 (0.98) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 | |
| Homoeriodictyol SCHEMBL7535609 | 0.97 | CYP1A1 (0.98) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 | |
| SCHEMBL28464154 | 0.91 | CYP1A1 (0.87) | CYP1A1CYP1A2CYP1B1POLBCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198451-B2 | Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners | SYMRISE AG (DE) | 2015-12-01 | — | — | US | disclosed |
| EP-2220945-B1 | Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners | SYMRISE AG (DE) | 2013-03-27 | — | — | EP | disclosed |
| EP-2220945-A1 | Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners | Symrise GmbH & Co. KG (DE) | 2010-08-25 | — | — | EP | disclosed |
| US-20100151055-A1 | Aroma Composition to Reduce or Suppress Undesirable Bitter and Astringent Taste Impressions of Sweeteners | SYMRISE GMBH & CO. KG (DE) | 2010-06-17 | — | — | US | disclosed |